FIGURE

Fig. S4

ID
ZDB-FIG-140703-14
Publication
Leitch et al., 2014 - Basal body proteins regulate Notch signaling via endosomal trafficking
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Fig. S4

Notch1 localization in ciliated and unciliated cells and suppression of Notch-inhibited cell type markers in bbs4 morphants. (A) hTERT-RPE1 cells doubled immunostained for detection of NOTCH1 (green) and ARL13B (red) and transfected with or without shBBS4. 40X magnification. Cilia in ciliated cells (+) magnified in inset boxes. Scale bars = 20 μm. (B) Expression of neurogenin1 in control MO-, bbs4 MO- and tsg101 MO-injected embryos at 24 hpf detected by whole mount in situ hybridization. (C) Expression of shippo1 in control MO-, bbs4 MO- and tsg101 MO-injected embryos at 24 hpf. Insets indicate magnification of dashed boxes.

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-5

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.