FIGURE

Fig. 3

ID
ZDB-FIG-140506-48
Publication
Pavlou et al., 2014 - Pleiotropic effects of Sox2 during the development of the zebrafish epithalamus
Other Figures
All Figure Page
Back to All Figure Page
Fig. 3

Knockdown of sox2 results in upregulation of neurogenesis.

(A–B) Neurogenesis is increased in sox2 morphants, as judged by Isl1 expression. (C) Average number of Isl1-positive cells in control (purple bar) and sox2 morphants (orange bar), at 24 and 28 hpf. (D–E) At 3–4 ss, two flh-domains are observed on either side of the neural plate. (F–G) By 7–8 ss, the two domains fuse to form the presumptive pineal gland. (H–K) In sox2 morphants, flh is expressed in broader domains in relation to control siblings. Scale bars = 25 μm, (A–B) confocal maximum projections, (C) error bars represent ± standard error, ** = p-value <0.001 (MWU test). (J,L,N,P) dorsal views with anterior to the top, (K,M,O,Q) frontal views. See also Figure S2–S3.

Expression Data
Gene:
Antibody:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: 1-4 somites to Prim-5

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One