FIGURE

Fig. 2

ID
ZDB-FIG-140422-70
Publication
Superina et al., 2014 - Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry
Other Figures
All Figure Page
Back to All Figure Page
Fig. 2

MZjek have a dysmorphic heart and reduced ventricular populations. (A,B) Lateral views of hearts stained with MF20 (red) and S46 (green) antibodies to visualize the ventricle and atrium of 48 hpf embryos. MF20 marks the entire heart and S46 is atrium specific. In these superimposed images MF20+S46- ventricle is red and MF20+S46+ atrium appears yellow. (A) Wildtype heart with two distinct chambers. (B) MZjek display a dysmorphic heart, with a misshapen atrium and a strung out ventricle (N=9). (C–F) amhc and vmhc expression in wildtype (C,E) and MZjek (D,F) at the 20-somite stage. MZjek mutants exhibit reduced expression of vmhc when compared to similarly staged wildtype embryos (N=25, 36 respectively).

Expression Data
Genes:
Antibodies:
Fish:
Anatomical Terms:
Stage Range: 20-25 somites to Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 387(2), Superina, S., Borovina, A., and Ciruna, B., Analysis of maternal-zygotic ugdh mutants reveals divergent roles for HSPGs in vertebrate embryogenesis and provides new insight into the initiation of left-right asymmetry, 154-166, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.