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General Information
ZIRC
ZFIN ID: ZDB-FIG-140306-18
Banjo et al., 2013 - Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21. Nature communications   4:1978 Full text @ Nat. Commun.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP y1Tg standard conditions Protruding-mouth atrial endocardium cell IHC
Protruding-mouth atrioventricular canal endocardium cell IHC
Protruding-mouth endocardial cushion IHC
Protruding-mouth endocardium cell IHC
Protruding-mouth ventricular endocardium cell IHC
y1Tg chemical treatment: pharmaceutical Protruding-mouth atrial endocardium cell IHC
Protruding-mouth atrioventricular canal endocardium cell IHC
Protruding-mouth endocardial cushion IHC
Protruding-mouth endocardium cell IHC
Protruding-mouth ventricular endocardium cell IHC
y1Tg + MO1-mir21-1 + MO1-mir21-2 standard conditions Protruding-mouth atrial endocardium cell IHC
Protruding-mouth atrioventricular canal endocardium cell IHC
Protruding-mouth endocardial cushion IHC
Protruding-mouth endocardium cell IHC
Protruding-mouth ventricular endocardium cell IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-mir21-1 + MO1-mir21-2 standard conditions Long-pec blood cell accumulation yolk anatomical surface, abnormal
Long-pec blood circulation decreased process quality, abnormal
Long-pec heart decreased width, abnormal
Long-pec heart looping arrested, abnormal
Long-pec hindbrain hypoplastic, abnormal
WT + MO2-mir21-1 + MO3-mir21-2 standard conditions Long-pec blood cell accumulation yolk anatomical surface, abnormal
Long-pec blood circulation decreased process quality, abnormal
Long-pec heart decreased width, abnormal
Long-pec heart looping arrested, abnormal
Long-pec hindbrain hypoplastic, abnormal
y1Tg chemical treatment: pharmaceutical Protruding-mouth endocardial cushion aplastic, abnormal
Protruding-mouth heart valve development disrupted, abnormal
y1Tg + MO1-mir21-1 + MO1-mir21-2 standard conditions Protruding-mouth endocardial cushion aplastic, abnormal
Protruding-mouth heart valve development disrupted, abnormal
Full text @ Nat. Commun.