ZFIN ID: ZDB-FIG-131107-4
Neal et al., 2013 - H. pylori Virulence Factor CagA Increases Intestinal Cell Proliferation by Wnt Pathway Activation in a Transgenic Zebrafish Model. Disease models & mechanisms   6(3):802-10 Full text @ Dis. Model. Mech.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Days 14-20

Fig. 4

CagA-dependent overproliferation of the intestinal epithelium requires tcf4. Intestinal epithelial cell proliferation at 15 dpf. Bars represent proliferation (mean ± s.e.m.) as a percentage of wild-type; n=10, *P<0.05 using one-way ANOVA with Tukey’s test.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
b1232Tg standard conditions Days 14-20 epithelial cell proliferation increased occurrence, abnormal
Days 14-20 intestinal epithelial cell proliferative, abnormal
tcf7l2zf55/zf55 standard conditions Days 14-20 epithelial cell proliferation process quality, normal
Days 14-20 intestinal epithelial cell proliferative, normal
tcf7l2zf55/zf55; b1232Tg standard conditions Days 14-20 epithelial cell proliferation process quality, normal
Days 14-20 intestinal epithelial cell proliferative, normal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.