ZFIN Figure: Neal et al., 2013, Fig. 4

ZFIN ID: ZDB-FIG-131107-4

ZFIN ID: ZDB-FIG-131107-4

Neal et al., 2013 - H. pylori Virulence Factor CagA Increases Intestinal Cell Proliferation by Wnt Pathway Activation in a Transgenic Zebrafish Model. Disease models & mechanisms 6(3):802-10 Full text @ Dis. Model. Mech.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	tcf7l2^zf55/zf55 b1232Tg tcf7l2^zf55/zf55; b1232Tg
Observed In:	epithelial cell proliferation intestinal epithelial cell
Stage:	Days 14-20

Fig. 4

CagA-dependent overproliferation of the intestinal epithelium requires tcf4. Intestinal epithelial cell proliferation at 15 dpf. Bars represent proliferation (mean ± s.e.m.) as a percentage of wild-type; n=10, *P<0.05 using one-way ANOVA with Tukey’s test.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
b1232Tg	standard conditions	Days 14-20	epithelial cell proliferation increased occurrence, abnormal
		Days 14-20	intestinal epithelial cell proliferative, abnormal
tcf7l2^zf55/zf55	standard conditions	Days 14-20	epithelial cell proliferation process quality, normal
		Days 14-20	intestinal epithelial cell proliferative, normal
tcf7l2^zf55/zf55; b1232Tg	standard conditions	Days 14-20	epithelial cell proliferation process quality, normal
		Days 14-20	intestinal epithelial cell proliferative, normal

Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.