FIGURE
Fig. 7
- ID
- ZDB-FIG-130509-4
- Publication
- Dabir et al., 2013 - A small molecule inhibitor of redox-regulated protein translocation into mitochondria
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Fig. 7
Embryos (3 hpf) were treated with 2.5 μM MitoBloCK-6 (B, E, and H) or 1% DMSO (A, D, and G) or embryos were injected with an ATG morpholino against ALR (C and F). Development was visualized by microscopy at 72 hpf (A–C). Erythrocytes were visualized by o-dianisidine staining at 72 hpf (D–F); arrows indicate regions of red blood cell accumulation in wild-type fish. Fluorescence microscopy of zebrafish hearts (72 hpf) that contained a mitochondrial-targeted DsRed included embryos treated with 1% DMSO (G), 2.5 μM MitoBloCK-6 (H), and buffer only (I). |
Expression Data
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| Fish: | |
| Condition: | |
| Anatomical Term: | |
| Stage: | Protruding-mouth |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Condition: | |
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Cell, 25(1), Dabir, D.V., Hasson, S.A., Setoguchi, K., Johnson, M.E., Wongkongkathep, P., Douglas, C.J., Zimmerman, J., Damoiseaux, R., Teitell, M.A., and Koehler, C.M., A small molecule inhibitor of redox-regulated protein translocation into mitochondria, 81-92, Copyright (2013) with permission from Elsevier. Full text @ Dev. Cell