header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-121130-6
Tsetskhladze et al., 2012 - Functional assessment of human coding mutations affecting skin pigmentation using zebrafish. PLoS One   7(10):e47398 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. S1 Injection of human mRNAs fail to rescue albino. (A) Wild-type zebrafish slc45a2 mRNA (1400 pg) injected into albino embryos rescues pigmentation (arrows) while SLC45A2 mRNA of human (B) ancestral (L374) (1400 pg) and (C) derived (L374F) (1400 pg) alleles do not. Scale bar 300 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-slc45a2 standard conditions Long-pec melanocyte decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One