ZFIN ID: ZDB-FIG-120306-4
Jiang et al., 1996 - Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. Development (Cambridge, England)   123:205-216
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibodies:
Fish:
Anatomical Terms:
Stage Range: Prim-5 to Prim-25
PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-5 to Prim-25

Fig. 4

Some cell types are decreased in witta52b. C and D are rostral to the top. A, B are lateral views; C-H are dorsal views. Wildtype (A) and mutant (B) embryos labeled with zn-5 mAb at 36 hpf. The dorsal hindbrain neurons (arrowheads; Trevarrow et al., 1990) are decreased in mutant embryos. The pharyngeal endoderm (asterisks; Schilling and Kimmel, 1994) is not affected. The pharyngeal endoderm in B is out of focus. Wildtype (C,E) and mutant (D,F) embryos labeled with zrf-1 mAb. C,D are at 24 hpf; E,F are at 38 hpf. Radial glial fibers in the retina (Westerfield, 1994) and hindbrain (Trevarrow et al., 1990) are decreased. TRP-2 expression pattern of wild-type (G) and mutant (H) embryos in the anterior trunk at 24 hpf. The labeled melanophores (arrows) are decreased in H. Bar, 125 µm (A-D); 100 µm (E-H).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dct WT standard conditions Prim-5 trunk melanocyte ISH
mib1ta52b/ta52b standard conditions Prim-5 trunk melanocyte ISH
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
zn-5 IHC WT standard conditions Prim-25 hindbrain dorsal region
IHC Prim-25 pharyngeal epithelium
IHC mib1ta52b/ta52b standard conditions Prim-25 hindbrain dorsal region
IHC Prim-25 pharyngeal epithelium
zrf-1 IHC WT standard conditions Prim-5 optic cup radial glial cell
IHC Prim-25 hindbrain radial glial cell
IHC mib1ta52b/ta52b standard conditions Prim-5 optic cup radial glial cell
IHC Prim-25 hindbrain radial glial cell
Phenotype Details
Fish Conditions Stage Phenotype
mib1ta52b/ta52b standard conditions Prim-5 optic cup has fewer parts of type radial glial cell, abnormal
mib1ta52b/ta52b standard conditions Prim-5 trunk anterior region has fewer parts of type melanocyte, abnormal
mib1ta52b/ta52b standard conditions Prim-25 hindbrain has fewer parts of type radial glial cell, abnormal
mib1ta52b/ta52b standard conditions Prim-25 hindbrain dorsal region has fewer parts of type neuron, abnormal
mib1ta52b/ta52b standard conditions Prim-25 pharyngeal endoderm morphology, normal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright.