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General Information
ZIRC
ZFIN ID: ZDB-FIG-120302-5
Thomas et al., 2011 - The loss of vacuolar protein sorting 11 (vps11) causes retinal pathogenesis in a vertebrate model of syndromic albinism. Investigative ophthalmology & visual science   52(6):3119-28 Full text @ Invest. Ophthalmol. Vis. Sci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Antibodies:
Fish:
Anatomical Terms:
Stage: Days 7-13
PHENOTYPE:
Fish:
Observed In:
Stage: Days 7-13

Fig. 8 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-glul IHC AB standard conditions Days 7-13 Muller cell
IHC vps11wsu1/wsu1(AB) standard conditions Days 7-13 Muller cell
Ab2-pcna IHC AB standard conditions Days 7-13 ciliary marginal zone
IHC vps11wsu1/wsu1(AB) standard conditions Days 7-13 ciliary marginal zone
IHC Days 7-13 retinal pigmented epithelium
Ab2-rho IHC AB standard conditions Days 7-13 photoreceptor outer segment layer retinal rod cell
IHC vps11wsu1/wsu1(AB) standard conditions Days 7-13 photoreceptor outer segment layer retinal rod cell
Phenotype Details
Fish Conditions Stage Phenotype
vps11wsu1/wsu1(AB) standard conditions Days 7-13 Muller cell hypertrophic, abnormal
Days 7-13 photoreceptor outer segment layer collapsed, abnormal
Days 7-13 photoreceptor outer segment layer photoreceptor outer segment membrane displaced to photoreceptor outer segment layer vacuolar lumen, abnormal
Days 7-13 photoreceptor outer segment layer retinal rod cell vacuolated, abnormal
Days 7-13 retinal neural layer detached from retinal pigmented epithelium, abnormal
Days 7-13 retinal neural layer chromatin condensed, abnormal
Days 7-13 retinal pigmented epithelium morphology, abnormal
Days 7-13 retinal pigmented epithelium vacuolated, abnormal
Days 7-13 retinal pigmented epithelium chromatin condensed, abnormal
Days 7-13 retinal pigmented epithelium melanocyte immature, abnormal
Full text @ Invest. Ophthalmol. Vis. Sci.