ZFIN ID: ZDB-FIG-110826-1
Schwend et al., 2011 - Requirement of Npc1 and availability of cholesterol for early embryonic cell movements in Zebrafish. Journal of Lipid Research   52(7):1328-44 Full text @ J. Lipid Res.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes: foxd3, pcdh8, ta
Fish: WT, WT + MO1-npc1
Knockdown Reagent: MO1-npc1
Anatomical Terms: notochord, segmental plate, tail bud, whole organism anterior region
Stage: 5-9 somites
PHENOTYPE:
Fish: WT + MO1-npc1
Knockdown Reagent: MO1-npc1
Observed In: cell death, lateral mesoderm, notochord, segmental plate, whole organism
Stage Range: 5-9 somites to 26+ somites

Fig. 9 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
foxd3 WT control 5-9 somites whole organism anterior region ISH
WT + MO1-npc1 standard conditions 5-9 somites whole organism anterior region ISH
pcdh8 WT control 5-9 somites segmental plate ISH
WT + MO1-npc1 standard conditions 5-9 somites segmental plate ISH
ta WT control 5-9 somites notochord ISH
5-9 somites tail bud ISH
WT + MO1-npc1 standard conditions 5-9 somites notochord ISH
5-9 somites tail bud ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-npc1 standard conditions 5-9 somites lateral mesoderm increased width, abnormal
5-9 somites notochord increased width, abnormal
5-9 somites segmental plate increased width, abnormal
5-9 somites whole organism decreased length, abnormal
26+ somites cell death increased occurrence, abnormal
26+ somites whole organism decreased length, abnormal
Full text @ J. Lipid Res.