ZFIN ID: ZDB-FIG-110317-45
Li et al., 2010 - Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling. American journal of human genetics   87(6):757-767 Full text @ Am. J. Hum. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Anatomical Terms:
Stage Range: Prim-5 to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Long-pec to Day 5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
chsy1 WT standard conditions Prim-5 floor plate ISH
Prim-5 median fin fold stratified keratinized epithelial stem cell ISH
Prim-5 myoseptum ISH
Long-pec mandibular arch skeleton ISH
Long-pec neurocranium chondrocyte ISH
Long-pec pars superior ear epithelium ISH
Long-pec pectoral fin ISH
Long-pec pharyngeal arch 2 skeleton ISH
Long-pec pharyngeal epithelium ISH
Protruding-mouth pars superior ear epithelium ISH
sox9a WT standard conditions Long-pec ethmoid cartilage ISH
Long-pec mandibular arch skeleton ISH
Long-pec pharyngeal arch 2 skeleton ISH
Long-pec trabecula cranii ISH
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
zn-5 IHC WT standard conditions Long-pec pharyngeal epithelium
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-chsy1 standard conditions Long-pec notochord undulate, abnormal
Protruding-mouth pectoral fin fold decreased size, abnormal
Protruding-mouth pectoral fin fold variability of size, abnormal
Day 4 optic fissure present, abnormal
Day 4 optic furrow open, abnormal
Day 5 ethmoid cartilage malformed, abnormal
Day 5 eye fused with eye, abnormal
Day 5 forebrain medial region aplastic, abnormal
Day 5 head bulbous, abnormal
Day 5 notochord degenerate, abnormal
Day 5 trabecula cranii malformed, abnormal
Day 5 ventral mandibular arch protruding, abnormal
Day 5 whole organism decreased length, abnormal
WT + MO2-chsy1 + MO4-tp53 standard conditions Long-pec notochord undulate, abnormal
Protruding-mouth pectoral fin fold decreased size, abnormal
Protruding-mouth pectoral fin fold variability of size, abnormal
Day 4 optic fissure present, abnormal
Day 4 optic furrow open, abnormal
Day 5 ethmoid cartilage malformed, abnormal
Day 5 eye fused with eye, abnormal
Day 5 forebrain medial region aplastic, abnormal
Day 5 head bulbous, abnormal
Day 5 notochord degenerate, abnormal
Day 5 trabecula cranii malformed, abnormal
Day 5 ventral mandibular arch protruding, abnormal
Day 5 whole organism decreased length, abnormal
Full text @ Am. J. Hum. Genet.