ZFIN ID: ZDB-FIG-110221-24
Johnson et al., 2011 - mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell. Developmental Biology   350(2):405-413 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Protruding-mouth

Fig. 5 mitfa is required at multiple steps in melanocyte development. A) mitfa expression persists at restrictive temperature. Wild-type and mitfafh53 larvae are shown. B) No dct is expressed in neural crest cells when held at restrictive temperature, but retinal expression of dct is not affected. Wild-type, mitfaw2, mitfafh53, and mitfavc7 larvae are shown. Embryos were treated with 0.2 mM PTU to suppress melanin synthesis. All larvae are at the equivalent of 82 h at standard temperature.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dct WT heat shock Protruding-mouth melanocyte ISH
Protruding-mouth retinal pigmented epithelium ISH
mitfavc7/vc7 heat shock Protruding-mouth retinal pigmented epithelium ISH
mitfaw2/w2 heat shock Protruding-mouth retinal pigmented epithelium ISH
mitfa WT heat shock Protruding-mouth head pigment cell ISH
mitfavc7/vc7 heat shock Protruding-mouth melanocyte ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 350(2), Johnson, S.L., Nguyen, A.N., and Lister, J.A., mitfa is required at multiple stages of melanocyte differentiation but not to establish the melanocyte stem cell, 405-413, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.