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ZIRC
ZFIN ID: ZDB-FIG-101122-35
Nowak et al., 2005 - Perp is required for tissue-specific cell survival during zebrafish development. Cell death and differentiation   12(1):52-64 Full text @ Cell Death Differ.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Fig. 6 Loss of Perp causes tissue degeneration. All images show live embryos at 48 hpf, either injected with a perp-specific antisense MO (perp MO) (a,c,e,g), or the four mismatch control MO (4 mm) (b,d,f,h). (a,b) Overviews over entire embryos. (c–f) Higher magnifications of the tail region, (c,d) lateral views, (e,f) ventral views. The morphology of cells of the median fin fold and the notochord are changed in morphants (c; arrow points to roundly shaped cell), as compared to control embryos (d). The same is true for the trunk skin (e,f). (g,h) Dorsal view on the pectoral fins. Abbreviations: epi, skin; pf, pectoral fin; tf, tail fin

Gene Expression DetailsNo data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-perp standard conditions Long-pec caudal fin collapsed, abnormal
Long-pec fin epithelial cell disorganized, abnormal
Long-pec integument epithelial cell disorganized, abnormal
Long-pec notochord degenerate, abnormal
Long-pec notochord epithelial cell circular, abnormal
Long-pec notochord epithelial cell disorganized, abnormal
Long-pec pectoral fin decreased length, abnormal
Long-pec pectoral fin malformed, abnormal
Long-pec post-vent region decreased length, abnormal
Long-pec trunk integument rough, abnormal
Long-pec whole organism decreased length, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Cell death and differentiation for permission to reproduce figures from this article. Please note that this material may be protected by copyright.
ZFIN also wishes to thank Matthias Hammerschmidt for permission to reproduce figures from this article.
Full text @ Cell Death Differ.