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General Information
ZIRC
ZFIN ID: ZDB-FIG-090122-11
Dong et al., 2008 - Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas. Genes & Development   22(11):1445-1450 Full text @ Genes & Dev.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Protruding-mouth
PHENOTYPE:
Fish:
Observed In:
Stage: High-pec

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP jh1Tg standard conditions Prim-25 pancreatic bud IFL
High-pec pancreatic bud IFL
ptf1as922/s922; jh1Tg standard conditions Prim-25 pancreatic bud IFL
High-pec pancreatic bud IFL
GFP ptf1as922/s922; s854Tg standard conditions High-pec digestive system IFL
Protruding-mouth digestive system IFL
s854Tg standard conditions High-pec digestive system IFL
Protruding-mouth digestive system IFL
nkx6.1 jh1Tg standard conditions Prim-25 pancreatic bud IHC
High-pec pancreatic bud IHC
Protruding-mouth pancreatic duct IHC
ptf1as922/s922; jh1Tg standard conditions Prim-25 posterior pancreatic bud IHC
High-pec pancreatic bud IHC
Protruding-mouth pancreatic duct IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-pan-Cadherin IHC jh1Tg standard conditions Protruding-mouth pancreatic duct plasma membrane
IHC ptf1as922/s922; jh1Tg standard conditions Protruding-mouth pancreatic duct plasma membrane
Ab2-ins IHC ptf1as922/s922; s854Tg standard conditions High-pec posterior pancreatic bud
IHC Protruding-mouth endocrine pancreas
IHC s854Tg standard conditions High-pec posterior pancreatic bud
IHC Protruding-mouth endocrine pancreas
Ab2-isl IHC ptf1as922/s922; s854Tg standard conditions High-pec posterior pancreatic bud
IHC Protruding-mouth endocrine pancreas
IHC s854Tg standard conditions High-pec posterior pancreatic bud
IHC Protruding-mouth endocrine pancreas
Ab3-prox1 IHC jh1Tg standard conditions Prim-25 anterior pancreatic bud
IHC Prim-25 liver
IHC Prim-25 posterior pancreatic bud
IHC High-pec anterior pancreatic bud
IHC High-pec liver
IHC High-pec posterior pancreatic bud
IHC ptf1as922/s922; jh1Tg standard conditions Prim-25 liver
IHC Prim-25 posterior pancreatic bud
IHC High-pec anterior pancreatic bud
IHC High-pec liver
IHC High-pec posterior pancreatic bud
Phenotype Details
Fish Conditions Stage Phenotype
ptf1as922/s922; jh1Tg standard conditions High-pec exocrine pancreas development delayed, abnormal
ptf1as922/s922; s854Tg standard conditions High-pec exocrine pancreas development disrupted, abnormal
Full text @ Genes & Dev.