FIGURE

Fig. 6

ID
ZDB-FIG-080828-87
Publication
Kim et al., 2008 - Notch-regulated oligodendrocyte specification from radial glia in the spinal cord of zebrafish embryos
Other Figures
All Figure Page
Back to All Figure Page
Fig. 6

Notch signaling is required to maintain radial glial cells during embryonic development. All panels show transverse sections of spinal cord with dorsal upward. A-C: Tg(olig2:egfp) larvae labeled with anti-Zrf-1 antibody (red) at 6 days postfertilization (dpf). Control (A), DAPT treatment begun at 32 hours postfertilization (hpf). (B), and DAPT treatment begun at 50 hpf (C). Arrows indicate Zrf-1+ enhanced green fluorescent protein-positive (EGFP+) radial glial cells, and arrowheads indicate EGFP+ oligodendrocyte lineage cells. D-F: A 3 dpf Tg(hsp70l:GAL4);Tg(UAS:myc-Notch1a-intra) larvae labeled with Zrf-1 antibody; control (D), heat induction at 24 hpf (E), and heat induction at 50 hpf (F). G,H: A 3 dpf larvae probed to detect her4 expression by in situ RNA hybridization. Control (G) and DAPT treatment begun at approximately 50 hpf (H). Scale bar = 20 μM.

Expression Data
Genes:
Antibody:
Fish:
Conditions:
Anatomical Terms:
Stage Range: Protruding-mouth to Day 6

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.