FIGURE

Fig. 6

ID

ZDB-FIG-080715-47

Publication

Martin et al., 2008 - Regulation of canonical Wnt signaling by Brachyury is essential for posterior mesoderm formation

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Fig. 6

Ntl/Bra Maintains wnt8 and wnt3a Expression

(A-P) wnt8 and (Q-X) wnt3a expression at the indicated stages in uninjected and MO2-injected wild-type siblings and ntl mutants. Embryos are shown from a (A–D) ventral view with animal pole to the top, (E-H) vegetal view with dorsal to the right, and (I-X) posterior view with dorsal to the top. Arrowheads mark wnt expression domains. What appears to be very light staining around the edge of the embryo in (H) is caused by an edge effect and is not specific.

Expression Data

Genes:	wnt3a wnt8a
Fish:	WT tbxta^b195/b195 WT + MO2-tbxtb tbxta^b195/b195 + MO2-tbxtb
Knockdown Reagent:	MO2-tbxtb
Anatomical Terms:	margin mesoderm paraxial mesoderm
Stage Range:	Shield to Bud

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 15(1), Martin, B.L., and Kimelman, D., Regulation of canonical Wnt signaling by Brachyury is essential for posterior mesoderm formation, 121-133, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell