FIGURE

Fig. 2

ID
ZDB-FIG-080701-31
Publication
Mara et al., 2008 - Two deltaC splice-variants have distinct signaling abilities during somitogenesis and midline patterning
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Fig. 2

deltaCtv2 does not signal effectively during somitogenesis. (A) qPCR showing the relative abundance of deltaCtv2 in 15 somite embryos of various genetic backgrounds. Levels of deltaCtv2 increase significantly in morpholino (mo) injected embryos. The amount of deltaCtv2 mRNA is graphed as a percentage of total deltaC mRNA. (B–C) titin staining marks the somite boundaries of deltaC+/- embryos. The first disrupted somite border in a morpholino injected embryo is indicated by the arrow in (C). (D) The average number of somites formed in each experimental condition. n = 93, 102, 73, 115 from top to bottom. (E–F) The onset of border defects in deltaD-/- embryos is shifted anteriorly in morpholino injected embryos. Arrows indicate the first abnormal border. (G) The average number of somites formed in each experimental condition. n = 73, 91, 84, 139, 99 from top to bottom. Two different sets of mutant and sibling embryos were used for the experiments marked in red and yellow. Error bars indicate standard deviation.

Expression Data
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: 26+ somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: 26+ somites

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 318(1), Mara, A., Schroeder, J., and Holley, S.A., Two deltaC splice-variants have distinct signaling abilities during somitogenesis and midline patterning, 126-132, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.