ZFIN ID: ZDB-FIG-070219-38
Uechi et al., 2006 - Ribosomal protein gene knockdown causes developmental defects in zebrafish. PLoS One   1(1):e37 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. 4 Similarities between the Clinical Features of Human Brain Diseases and Defects in Zebrafish Morphants (A) Common features shared between Abidi X-linked mental retardation and microhydranencephaly are listed on the left and the corresponding changes in rps4 and rps15a morphants are indicated on the right. (B) Telencephalon hypoplasia is seen in rps4 morphants, and reduction in size and deformity of the telencephalon is apparent in rps15a morphants (white arrows). Unclear subdivisions of the brain and flattened foreheads (arrowheads) can be seen in lateral views of these morphants.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-rps15a standard conditions Prim-5 head flat, abnormal
Prim-5 telencephalon decreased size, abnormal
Prim-5 telencephalon deformed, abnormal
AB + MO1-rps4x standard conditions Prim-5 head flat, abnormal
Prim-5 telencephalon decreased size, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One