ZFIN ID: ZDB-FIG-070219-37
Uechi et al., 2006 - Ribosomal protein gene knockdown causes developmental defects in zebrafish. PLoS One   1(1):e37 Full text @ PLoS One
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. 3 Schematic Representation of the Extent of Abnormalities in Brain and Body Trunk (A) 6 parts of the brain, 3 parts of the body trunk, and a dorsal view of the trunk are indicated in wild type embryo. a, optic tectum; b, 4th ventricle; c, midbrain-hindbrain boundary; d, anterior part of head; e, rhombencephalon; f, telencephalon; g, body along yolk sac extension; h, tail; i, tip of tail; j, dorsal view of the trunk. (B) The deformations were assessed using a 3-level severity scale; dark gray indicates a severe effect, light gray indicates a mild effect, and white represents no apparent effect. Detailed information and images of the abnormalities in the morphants are available at the zebrafish database (http://zebrafish.med.miyazaki-u.ac.jp).

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO1-rpl11 standard conditions Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin deformed, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otic placode shape, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 trunk bent, abnormal
AB + MO1-rpl24 standard conditions Prim-5 ball increased size, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 extension deformed, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otic placode shape, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 telencephalon deformed, abnormal
AB + MO1-rpl28 standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 extension deformed, abnormal
Prim-5 fin deformed, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 midbrain hindbrain boundary deformed, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 otic placode aplastic, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otolith organ decreased size, abnormal
Prim-5 otolith organ deformed, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 telencephalon deformed, abnormal
AB + MO1-rpl35 standard conditions Prim-5 ball increased size, abnormal
Prim-5 ball opaque, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode aplastic, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otolith organ deformed, abnormal
Prim-5 post-vent region deformed, abnormal
Prim-5 retina decreased size, abnormal
AB + MO1-rpl35a standard conditions Prim-5 ball increased size, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 extension deformed, abnormal
Prim-5 fin deformed, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 notochord undulate, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otic placode shape, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 telencephalon hypoplastic, abnormal
Prim-5 trunk undulate, abnormal
AB + MO1-rpl36a standard conditions Prim-5 ball increased size, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 extension deformed, abnormal
Prim-5 fin deformed, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain opaque, abnormal
Prim-5 lens increased size, abnormal
Prim-5 nucleate erythrocyte decreased amount, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 otic placode decreased size, abnormal
AB + MO1-rpl38 standard conditions Prim-5 cerebellum decreased thickness, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin deformed, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode aplastic, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 tegmentum opaque, abnormal
Prim-5 telencephalon deformed, abnormal
AB + MO1-rpl5a standard conditions Prim-5 fourth ventricle morphology, abnormal
Prim-5 hindbrain morphology, abnormal
Prim-5 midbrain hindbrain boundary morphology, abnormal
Prim-5 optic tectum morphology, abnormal
Prim-5 post-vent region morphology, abnormal
AB + MO1-rpl5a + MO1-rpl5b standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 fin deformed, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 retina decreased size, abnormal
AB + MO1-rpl5b standard conditions Prim-5 brain morphology, normal
Prim-5 trunk morphology, normal
AB + MO1-rpl6 standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum decreased thickness, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain increased size, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 notochord undulate, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 trunk bent, abnormal
AB + MO1-rplp0 standard conditions Prim-5 cerebellum decreased thickness, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
AB + MO1-rplp1 standard conditions Prim-5 brain morphology, normal
Prim-5 trunk morphology, normal
AB + MO1-rplp2l standard conditions Prim-5 ball increased size, abnormal
Prim-5 ball opaque, abnormal
Prim-5 cerebellum decreased thickness, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 notochord bent, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otolith organ decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 tegmentum opaque, abnormal
Prim-5 telencephalon hypoplastic, abnormal
AB + MO1-rps15 standard conditions Prim-5 cerebellum decreased thickness, abnormal
Prim-5 eye color, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region morphology, abnormal
Prim-5 retina decreased size, abnormal
AB + MO1-rps15a standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum decreased thickness, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode aplastic, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 tegmentum opaque, abnormal
AB + MO1-rps19 standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum decreased thickness, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain morphology, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 nucleate erythrocyte decreased amount, abnormal
Prim-5 optic tectum aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode aplastic, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 otolith organ decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 tegmentum opaque, abnormal
AB + MO1-rps29 standard conditions Prim-5 ball deformed, abnormal
Prim-5 ball increased size, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased length, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 extension deformed, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain morphology, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 lens increased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 notochord bent, abnormal
Prim-5 nucleate erythrocyte decreased amount, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode aplastic, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
AB + MO1-rps3 standard conditions Prim-5 ball deformed, abnormal
Prim-5 ball opaque, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 extension deformed, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 fin decreased thickness, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle decreased size, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain aplastic, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 telencephalon hypoplastic, abnormal
AB + MO1-rps3a standard conditions Prim-5 ball increased size, abnormal
Prim-5 ball opaque, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 post-vent region curved, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 telencephalon hypoplastic, abnormal
Prim-5 trunk undulate, abnormal
AB + MO1-rps4x standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 hindbrain opaque, abnormal
Prim-5 hindbrain undulate, abnormal
Prim-5 lens decreased size, abnormal
Prim-5 midbrain aplastic, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 telencephalon hypoplastic, abnormal
Prim-5 trunk undulate, abnormal
AB + MO1-rps8a standard conditions Prim-5 ball increased size, abnormal
Prim-5 cerebellum aplastic, abnormal
Prim-5 extension decreased thickness, abnormal
Prim-5 fin aplastic, abnormal
Prim-5 forebrain protruding, abnormal
Prim-5 fourth ventricle increased size, abnormal
Prim-5 fourth ventricle opaque, abnormal
Prim-5 midbrain hindbrain boundary aplastic, abnormal
Prim-5 notochord bent, abnormal
Prim-5 optic tectum increased size, abnormal
Prim-5 optic tectum opaque, abnormal
Prim-5 otic placode decreased size, abnormal
Prim-5 post-vent region bent, abnormal
Prim-5 retina decreased size, abnormal
Prim-5 tegmentum opaque, abnormal
Prim-5 telencephalon morphology, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One