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ZFIN ID: ZDB-FIG-060808-223
Peng et al., 2006 - Lhx5 promotes forebrain development and activates transcription of secreted Wnt antagonists. Development (Cambridge, England)   133(16):3191-3200 Full text @ Development
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage: Bud

Fig. 2 Lhx5 partially rescues forebrain deficiencies induced by ectopic Wnt signaling. (A) lhx5 gain of function partially rescues the eyeless phenotype of wnt8a mRNA-injected embryos. Injected embryos were scored after the Prim-5 stage (24 hours post-fertilization). The percentages of embryos eyeless (blue) or with two eyes (green), or malformed as a result of dorsalization or injection (yellow), were measured. (B-D) lhx5 gain of function partially rescues eye development in mbl (axin1) mutants. Ventral views, rostral to the left. (E-G) lhx5 gain of function partially restores emx3 expression in mbl (axin1) mutants. Genotypes of mutant and partially rescued embryos were verified by RFLP. (H-J) lhx5 gain of function partially restores six3b expression in mbl (axin1) mutants. WT, wild-type embryos. Scale bar in J: 150 μm for B-D; 250 μm for E-J.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
emx3 WT standard conditions Bud neural keel ISH
axin1tm213/tm213 standard conditions Bud Not Detected neural keel ISH
six3b WT standard conditions Bud neural keel ISH
axin1tm213/tm213 standard conditions Bud neural keel ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development