FIGURE

Fig. 7

ID
ZDB-FIG-060522-52
Publication
Foucher et al., 2006 - Differentiation of cerebellar cell identities in absence of Fgf signalling in zebrafish Otx morphants
Other Figures
All Figure Page
Back to All Figure Page
Fig. 7

Early r1 rescue in fgf8-/-; OtxH embryos is independent of gbx2. Dorsal views, anterior towards the left showing efnb2a expression in wild-type (A, n=5/5), OtxH (B, n=8/9), wild type+SU5402 (C, n=12/15) or OtxH+SU5402 (D, n=18/23) embryos. The anteroposterior extent of r1 territory (arrows) is the same in OtxH with or without SU5402. Conversely, SU5402 treatment affects r5-7 development as previously reported (Maves et al., 2002). (E,F) Lateral views, anterior towards the left, of wild-type (E) and fgf8-/- (F) 8-somite stage embryos, showing double expression of otx2 (blue) and her5pac:egfp (red). (G-J) Lateral views, anterior towards the left, showing gbx2 expression in wild type (G), OtxH (H), fgf8-/- (I) or fgf8-/-; OtxH (J). gbx2 CNS expression is lost in fgf8-/- (arrows) and is not rescued in fgf8-/-; OtxH (out of 21 fgf8-/-; OtxH embryos, only five show a very faint rescue of Gbx2 expression in the very ventral metencephalic area). Asterisks indicate gbx2 expression in the epibranchial placode precursors.

Expression Data
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage Range: 5-9 somites to 10-13 somites

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development