FIGURE

Fig. 3

ID
ZDB-FIG-051214-17
Publication
Whitlock et al., 2005 - A role for foxd3 and sox10 in the differentiation of gonadotropin-releasing hormone (GnRH) cells in the zebrafish Danio rerio
Other Figures
All Figure Page
Back to All Figure Page
Fig. 3

Role of foxd3, sox10 and fgf8 in the development of midbrain gnrh2 cells. Dorsal views of whole-mount preparations, showing gnrh2 expression in the head of embryos at 35α1 hpf. (A-D) The effects of knockdown of foxd3 and sox10. (A) foxd3+sox10 mismatch control embryos, showing a normal complement of gnrh2 cells (arrows) (Gopinath et al., 2004. foxd3 (B) and sox10 (C) morphant animals showed significantly fewer gnrh2 cells than did mismatch control embryos (A), whereas animals injected with both foxd3 and sox10 MOs (D) showed a complete loss of gnrh2 cells (see Table 1). (E,F) Role of fgf8 in gnrh2 development. (E) Expression of gnrh2 in an ace non-mutant sibling control. (F) ace mutant embryo showing the normal number of gnrh2-expressing cells (see Table 1). Scale bar: 100 µm.

Expression Data
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Prim-15

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development