FIGURE

Fig. 5

ID
ZDB-FIG-041108-5
Publication
Hans et al., 2004 - Pax8 and Pax2a function synergistically in otic specification, downstream of the Foxi1 and Dlx3b transcription factors
Other Figures
All Figure Page
Back to All Figure Page
Fig. 5

Pax8 mediates the early Fgf-dependent induction of pax2a expression. In fgf8– mutant embryos at the five-somite stage, the preotic pax2a expression is reduced in size (B) compared with wildtype embryos of the same age (A). fgf8– mutant embryos after Pax8 depletion show an even further reduction of preotic pax2a expression (C). The defects in Pax2a expression are later manifested in a slightly reduced ear in fgf8– mutant embryos (E) or more severely reduced ear in fgf8– embryos depleted of Pax8 (F) in comparison with wildtype embryos at 50 h (D). (A-C) Dorsal views, anterior towards the top; (D-F) side views, anterior towards the left, dorsal towards the top. Scale bar: 120 μm for A-C; 180 μm for D-F.

Expression Data
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: 5-9 somites

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development