CRISPR

CRISPR8-tp53

ID

ZDB-CRISPR-190417-21

Name

CRISPR8-tp53

Previous Names

None

Target

tp53 (1)

Sequence

5' - TGGTTCGAGCCACTGCCATC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hg91	tp53

Expression

Gene expression in Wild Types + CRISPR8-tp53

No data available

Phenotype

Phenotype resulting from CRISPR8-tp53

No data available

Phenotype of all Fish created by or utilizing CRISPR8-tp53

Phenotype	Fish	Conditions	Figures
whole organism mdm2 expression increased amount, abnormal	tp53^hg91/hg91	standard conditions	Fig. S9 from McElderry et al., 2019
whole organism tp53 expression absent, abnormal	tp53^hg91/hg91	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
head apoptotic process increased occurrence, abnormal	dhx15^hg92/hg92; tp53^hg91/hg91	standard conditions	Fig. 6 from McElderry et al., 2019
head apoptotic, abnormal	dhx15^hg92/hg92; tp53^hg91/hg91	standard conditions	Fig. 6 from McElderry et al., 2019
whole organism mdm2 expression increased amount, abnormal	dhx15^hg93/hg93; tp53^hg91/hg91	standard conditions	Fig. S9 from McElderry et al., 2019
male organism increased amount, abnormal	slx4^hg67/hg67; tp53^hg91/+	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
female organism absent, abnormal	slx4^hg67/hg67; tp53^hg91/+	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
male sex determination increased occurrence, abnormal	slx4^hg67/hg67; tp53^hg91/+	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
female sex determination decreased occurrence, abnormal	slx4^hg67/hg67; tp53^hg91/+	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
male sex determination occurrence, ameliorated	slx4^hg67/hg67; tp53^hg91/hg91	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
female organism amount, ameliorated	slx4^hg67/hg67; tp53^hg91/hg91	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
male organism amount, ameliorated	slx4^hg67/hg67; tp53^hg91/hg91	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018
female sex determination occurrence, ameliorated	slx4^hg67/hg67; tp53^hg91/hg91	standard conditions	Fig. 6 from Ramanagoudr-Bhojappa et al., 2018

Citations